Thant Zin's artistic odyssey commenced at the State School of Fine Art (Yangon) in 1979, where he delved into the world of painting through evening classes. Specialising in oil painting, he was guided by revered mentors including U Tun Kyaw, U Kyi, U Lun Gywe, U Mya Aye, and U Zaw Min. These luminaries instilled in him a profound understanding of art's language, nurturing his talents and shaping his unique perspective. Through meticulous strokes and a keen sense of composition, he masterfully captures the interplay of light and shadow, infusing his creations with depth and emotion that resonate with viewers. In 1992, Thant Zin established the Orient Art Gallery, Myanmar.

Thant Zin's artistic prowess found its voice in a series of exhibitions, including Colors of Maw Ra Waddy, Orient art Gallery, Myanmar (2015), Art Asia, Kuala Lumpur (2015), The Essence of Emotion Art Exhibition, Gallery 65, Myanmar (2016), Truth Beyond Beauty Exhibition, The Yangon Gallery, Myanmar (2017), Mood of Outdoor Art Exhibition, Ahla Thit Art Gallery, Myanmar (2019) and Orient Art Gallery Art Exhibition, Oriental Art Gallery, Myanmar (2023).